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The Crohn's Disease Activity Index or CDAI is a research tool used to quantify the symptoms of patients with Crohn's disease. This is of useful importance in research studies done on medications used to treat Crohn's disease; most major studies on newer medications use the CDAI in order to define response or remission of disease. As Crohn's disease is a disease with a variety of symptoms that affect quality of life, the quantification of symptoms may be of secondary importance to a quantitative assessment of the effect on quality of life. This has been addressed by the Inflammatory Bowel Disease Questionnaire (IBDQ) and other indices of quality of life for patients with Crohn's disease. ==Components of the index== The CDAI was developed by WR Best and colleagues from the Midwest Regional Health Center in Illinois, in 1976. The index consists of eight factors, each summed after adjustment with a weighting factor. The components of the CDAI and weighting factors are the following: * * the presence of joint pains (arthralgia) or frank arthritis * inflammation of the iris or uveitis * presence of erythema nodosum, pyoderma gangrenosum, or aphthous ulcers * anal fissures, fistulae or abscesses * other fistulae * fever during the previous week. Remission of Crohn's disease is defined as CDAI below 150. Severe disease was defined as a value of greater than 450.〔 Most major research studies on medications in Crohn's disease define response as a fall of the CDAI of greater than 70 points. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Crohn's Disease Activity Index」の詳細全文を読む スポンサード リンク
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